Epidemiology Research Platform

From NHANES Data to
Lancet-Quality Publication

Automated survey-weighted analysis, publication-ready figures, and manuscript generation. Transform months of epidemiological research into a reproducible, one-click pipeline.

$ python run.py --topic "BMI and hypertension" --cycles 2017-2018
 
☰ Step 1/8: Parsing research proposal...
🔎 Step 2/8: Mapping variables → BMXBMI, BPQ020, RIAGENDR...
📥 Step 3/8: Downloading NHANES 2017-2018 from CDC...
⚙️ Step 4/8: Processing & merging datasets (n=4,520)
📊 Step 5/8: Survey-weighted logistic regression (OR=1.87, 95%CI 1.52-2.29)
📈 Step 6/8: Generating Table 1, forest plots, Kaplan-Meier curves
📚 Step 7/8: PubMed search → 23 related articles retrieved
✍️ Step 8/8: Writing Lancet-format manuscript...
 
✔ Done! Results: output/bmi_hypertension/results.zip
0
NHANES Variables Indexed
0
Phenotype Presets
0
Survey Cycles (1999-2018)
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Pipeline Steps Automated

8-Step Automated Pipeline

From research question to submission-ready manuscript in one reproducible workflow

1

Parse Proposal

Upload a Word document or enter your research question. PICO/PECO framework automatically extracted using NLP.

2

Map Variables

Intelligent mapping from your concepts to 150+ NHANES variables across demographics, labs, questionnaires, and mortality data.

3

Download Data

Automated XPT file download from CDC NHANES FTP, with local parquet caching. Supports all 10 cycles from 1999-2018.

4

Process & Merge

Clean missing codes, recode variables, merge DEMO+LAB+Q datasets. Automatic survey weight adjustment for multi-cycle analysis.

5

Statistical Analysis

Survey-weighted descriptive stats, Rao-Scott chi-square, logistic/linear regression, subgroup analysis with proper SE estimation.

6

Tables & Figures

Lancet-standard Table 1 (baseline), regression tables, forest plots, correlation heatmaps, Kaplan-Meier curves. 300 DPI output.

7

Literature Search

Real-time PubMed search via NCBI E-utilities. Auto-retrieves related studies, formats Vancouver-style citations for your manuscript.

8

Write Manuscript

Generate a Lancet-format paper: structured abstract, methods with STROBE compliance, results with embedded tables, and discussion.

Why NHANES to Lancet?

Purpose-built for epidemiological research, not a generic data tool

🎯

Survey-Weighted Statistics

Proper NHANES complex survey design with MEC/interview weights, PSU, and strata. Not just “add weights to regression” — Taylor linearization SEs, Rao-Scott chi-square, and weight adjustment for multi-cycle pooling.

📈

Publication-Quality Output

300 DPI figures in Lancet color palette. Table 1 with means/SD or n/% by group. Forest plots with HR/OR and 95% CI. Correlation heatmaps. STROBE checklist compliance verification.

📚

150+ Variable Knowledge Base

Curated database of NHANES variables across 27 categories: demographics, body measures, blood pressure, labs, questionnaires, diet, physical activity, sleep, depression (PHQ-9), and mortality follow-up.

🤖

AI-Powered Paper Writing

DeepSeek LLM integration for Lancet-format manuscript generation. Structured abstract, methods section with exact statistical parameters, results narrative, and discussion with strengths/limitations.

🚀

10 Phenotype Presets

Pre-configured exposure/outcome/covariate sets for: obesity, diabetes, hypertension, dyslipidemia, CVD, smoking, depression, CKD, diet quality, and sleep disorders. One-click study setup.

📦

Reproducible Results

Every analysis produces a complete ZIP package: cleaned dataset, analysis scripts (Python + R), all tables/figures, generated manuscript, and a manifest with version info and parameters.

How We Compare

NHANES analysis requires specialized knowledge. We encode that knowledge into software.

CapabilityNHANES to LancetGeneric Stats ToolsManual Analysis
Automatic CDC data download✓——
Survey-weighted analysis✓Partial✓
NHANES variable knowledge base✓——
Lancet-format manuscript generation✓——
STROBE compliance check✓—Manual
PubMed literature integration✓——
Reproducible pipeline✓Partial—
Time to results~10 minutesHoursWeeks

Built For

Real epidemiological research scenarios, not toy examples

🏥

PhD Students & Postdocs

First NHANES paper without spending months learning survey design, SAS/STATA code, and Lancet formatting conventions.

🏧

Research Labs

Rapid hypothesis testing across multiple NHANES cycles. Batch-process several research questions with consistent methodology.

🌐

Public Health Institutions

Standardized, auditable analysis pipeline for population health surveillance. Reproducible reports for policy stakeholders.

Pricing

Choose the plan that fits your research workflow

Starter

$0/mo

For individual researchers exploring NHANES

  • 1 NHANES cycle per analysis
  • Basic descriptive statistics
  • Table 1 generation
  • 3 analyses per month
  • Community support
Get Started Free

Enterprise

$199/mo

For institutions and CROs

  • All Professional features
  • Custom variable mapping
  • Multi-study batch processing
  • Dedicated account manager
  • SLA guarantee
  • On-premise deployment option
Contact Sales

Ready to accelerate your research?

Join researchers using NHANES to Lancet for faster, reproducible epidemiological analysis.

Try Live Demo View on GitHub